Quality Control Analysis of Dry Syrup Products in the Filling and Cramping Process using the DMAIC Method in Pharmaceutical Companies

Abstract

The main factor that companies, especially pharmaceutical companies, must consider is producing quality products to compete. During the production process of Dry Syrup for pharmaceutical companies, several quality defects were found, such as Alcap loss, alcap torn, alcap scratched, alcap broken 1 ring, alcap broken 2 rings, bottles without alcap, alcap dented, and underweight with the acquisition of a defect percentage exceeding the maximum company tolerance limit of 5% in the last six months, from October 2022 to March 2023. This research is focused on the problem of Alcap Loss and Underweight defect types because they are the dominant defects among all defect types. The DMAIC method is used to solve and reduce product quality defect problems. The proposed improvements given are making a standardized range for setting screw knives with points on how to set screw knives and adding filling weight inspection intervals with filling weight monitoring sheets. The results of the application of improvements using the DMAIC method and the application of proposed improvements reduce product defects by 40% and increase the sigma value from 3.40 to a value of 3.84.